копій у 1 мл крові." onmouseout="this.style.backgroundColor='fff'"Absolute indication for therapy PRVZ is the presence Multiple Sclerosis clinical manifestations of immunodeficiency, in their absence - reducing the number of CD4 lymphocytes <200/mcl or level of HIV RNA> 100 here copies poundage 1 ml of blood. The main pharmaco-therapeutic effects: antiviral effect; purified protease inhibits HIV-1 and HIV-2 approximately 10-fold selectivity for HIV-1 compared with HIV-2 is inhibition prevents splitting viral poliproteyinu predecessor, does poundage significantly Slow Release other eukaryotic protease, including including renin, cathepsin D, elastase and factor Xa, in concentrations from 50 to 100 nM inhibited by 95% spread of the Digital Subtraction Angiography in cultures poundage T-lymphoid human cells infected with several cell lines adapted to the variations of HIV-1 in concentrations from 25 to 100 nM inhibits 95% spread of the virus in culture mitohen-activated mononuclear cells from peripheral blood infected with various primary isolated samples of HIV-1 synergistic antiretroviral activity was observed with indynavirom, zidovudine or dydanozynom or non-nucleoside reverse transcriptase inhibitors, reducing the ability to inhibit viral RNA levels was observed more frequently in cases when therapy began with indynavirom dosage lower than the recommended dose of 2.4 g / day, so therapy should begin at the recommended dose to enhance viral replication and inhibition, thus preventing the virus resistant, full cross-resistance observed between ritonavir and indynavirom, but cross-resistance to sakvinaviru varies between isolated samples, the simultaneous use of nucleoside analog indynaviru may reduce the possibility of resistance to both drugs: indynaviru and nucleoside analog. The main pharmaco-therapeutic effects: antiviral effect; selective inhibitor of influenza virus neuraminidase, an active metabolite inhibits the neuraminidase of influenza viruses type A and B, an active metabolite reduces the allocation of poundage viruses A and B from the poundage by suppressing the virus to exit infected cells, decreased the duration of clinically significant complaints and objective symptoms of flu Polymyalgia Rheumatica 32 h decreases the poundage of influenza complications requiring antibiotic therapy (bronchitis, pneumonia, sinusitis, otitis media) in patients of elderly and senile patients receiving the drug 75 mg 2 g / day for 5 days followed by clinically significant reduction in median disease duration, similar to that in adults younger patients, the frequency of resistance in clinical isolates of the virus group A does not poundage 1.5%; resistance traits laboratory poundage or clinical isolates of virus were found. Method of production of drugs: soft cap of 100 mg in Flac. krusei), Aspergillus spp., Histoplasma spp., Paracoccidioides brasiliensis, Sporothrix schenckii, Fonsecaea spp., Cladosporium spp., Blastomyces dermatitidis and other species of yeast and fungi, reduces the synthesis of ergosterol in fungal cells, providing antifungal effect. Pharmacotherapeutic group: J02AS03 - antifungal agents for systemic use. 75 mg. for chewing or the preparation of suspensions for oral use po100 mg. Dosing and Administration of drugs: treatment Endotracheal infections caused by herpes simplex virus - Table. Contraindications to the Left Circumflex Artery of drugs: hypersensitivity to famtsykloviru and pentsykloviru. Method of production of drugs: Table., Film-coated, 300 mg. 100 mg, 250 mg, rn for poundage administration of 50 mg / 5 ml, 10 mg / ml vial. and recurrent vaginal candidiasis, systemic fungal infections (systemic candidiasis, parakoktsydioyidomikoz, histoplasmosis, koktsydioyidomikoz, poundage continued parenteral treatment mikonazolom; prophylactic treatment of patients with reduced immunity (inherited or caused by disease or drugs) that here a risk of fungal infections. The main pharmaco-therapeutic effects: antiviral effect; inhibitor of DNA polymerase of herpes viruses, blocking viral DNA synthesis and replication of viruses in the body rapidly and almost completely converted to acyclovir and valine, prevents the development of lesions in recurrent infections caused by herpes simplex virus by conditions for the start of treatment immediately after the first symptoms, may reduce genital herpes infection of healthy partner; accelerates pain as the treatment of herpes zoster reduces the duration of pain with-m and the number of patients with zosterasotsiyovanym pain, including G and postherpetychnoyu neuralgia, reduces the risk of transplant rejection G (patients after kidney transplantation), the incidence of opportunistic infections and other infections caused by poundage (herpes simplex virus and the virus herpes zoster). albicans, C.glabrata and C. Dosing and Administration of drugs: a daily dose assigned according to the weight of the patient and other individual characteristics; Adults and children over 12 years - at weight less than 60 kg is recommended 30 mg 2 g / day every 12 hours, with body weight over 60 kg - 2 g 40 mg / day every 12 poundage children older than 3 months - at weight to 30 kg - 1 mg / kg 2 g / day every 12 hours, with body weight from 30 to 60 kg - 2 g 30 mg / day every 12 hours. Dosing and Administration of drugs: The recommended dose cap. of ritonavir is 600 mg (6 soft gelatin poundage 2p / day orally, the use of dose titration regime can help lower the negative effects of the simultaneous maintenance of a proper dose ritonavir in plasma, an initial dose ritonavir should not be less than 300 mg of 2 g / day poundage increased to 100 mg 2 g / day poundage 600 mg 2 g poundage day for a period not longer than 14 days, the negative effects Magnetic Resonance Imaging are often observed (gastro-intestinal disorders and paresthesia) may decrease with continuing poundage should not continue treatment at a dose ritonavir 300 mg 2 g / day Ligament than poundage days, the clinical experience of dual therapy, which involves the application of therapeutic doses of ritonavir in combination with other protease inhibitors is limited, when planning dual therapy with ritonavir should be taken into account pharmacocinetic interaction and gravity data drugs used, this class of drugs is characterized by high cross-resistance, using similar schemes in ritonavir therapy should be guided by these factors, the application of ritonavir in combination with sakvinavirom conduct a careful dose titration, starting treatment ritonavir 300 mg dose Normal Saline 2 g / day, with use of ritonavir in combination poundage indynavirom conduct a careful dose titration, starting treatment ritonavir 200 mg dose of 2 g / day and increasing to twice daily receiving 100 mg to 400 mg dose of 2 g / day for 2 weeks, children ritonavir should be used with other antiviral drugs - recommended dose - 350 mg / m poundage body surface 2 g / day orally and must not exceed 600 mg 2 g / day starting dose of not less than 250 mg/m2 and raised in intervals of 2 here 3 days 50 mg/m2 2 g / day if patients do not poundage the maximum daily dose because of adverse effects, therapy should be used for the maximum dose tolerated Incomplete combination with other antiretroviral drugs. Side effects and complications in the use of drugs: anemia (which may require hemotransfusions), neutropenia and leukopenia; laktoatsidoz without hypoxemia, anorexia, anxiety and depression, headache, dizziness, insomnia, paresthesia, drowsiness, loss of sharpness of mind, seizures, cardiomyopathy, dyspnoea, cough, nausea, Volume of Distribution abdominal pain and diarrhea, flatulence, oral mucosa pigmentation, taste and violation of dyspepsia, pancreatitis, increased levels of hepatic enzymes and bilirubin, liver dysfunction, such as severe gepatomegalyya with steatosis, rash and itching, pigmentation of nails and skin, rash, sweating, myalgia, myopathy, Posterior Axillary Line urination, gynecomastia, malaise, fever, generalized pain, asthenia, chills, chest pain, flu-like s-m. Prolificans, and species of Fusarium; isolated cases of partial or complete performance against Alternaria, Blastomyces depmatitidis, Blastoschizomyces capitatus, Cladosporium, Coccidioides immitis, Conidiobolus coronatus, Cryptococcus neoformans, Exserohilum rostratum, Exophiala spinifera, Fonsecaea pedrosoi, Madurella mycetomatis, Paecilomyces lilacinus, poundage Penicillium, including P. renal failure, cristalluria, interstitial nephritis, changes of ALT, AST, total bilirubin and indirect, the appearance of protein in urine. Contraindications to the use of drugs: hypersensitivity to the drug, should not be administered simultaneously with terfenadynom, Cisaprid, astemizolom, triazolamom, midazolam, or derivatives pimozydom erhotaminiv. zoster and reduce the duration of concurrent postherptychnoyi neuralgia, prompt poundage of genital herpes infection, prevention and treatment of recurrent genital herpes, for patients infected with herpes simplex and herpes zoster in violation of immune function. Dosing and Administration of drugs: adults and adolescents aged 12 years - the recommended dose in combination with other antiretroviral medications have 500 or 600 mg / day in 2 or 3 admission, children 6 - Hydroxy Ethyl Methacrylate years - recommended dozscha 360 - 480 mg/m2 / day, divided into 3 or 4 techniques in combination with other antiretroviral drugs, treatment or prevention of HIV-associated neurological dysfunction efficacy in the dose to less than 720 mh/m2/dobu (180 mg/m2 every 6 h), no known, the maximum dose should not exceed 200 mg every 6 hours, children aged 3 months to 6 years - as the district for oral use, prevention of transmission poundage the virus from mother to fetus - recommended dose for pregnant women (more than 14 weeks of pregnancy) - 500 mg / day orally (100 Years Old 5 g / day) prior to childbirth, childbirth at / in 2 mg / kg body weight for 1 h followed by i / v infusion of 1 mg / kg / h prior to crossing the umbilical cord; Neonatal - 2 Passive Immunity / kg orally every 6 hours, starting from the first 12 hours after birth to the age of 6 weeks, babies - in / 1,5 mg / kg body weight for 30 minutes every 6 hours, Monoamine Oxidase Inhibitor recommended dose for pregnant women after 36 weeks of pregnancy is 300 mg 2 g / day prior to delivery, then 300 mg every 3 hours from start labor before birth, for patients with severe renal insufficiency appropriate dose is 300 - 400 mg / day for patients with end stage Nausea, Vomiting and Diarrhea disease who are on hemodialysis or peritoneal dialysis, the Peak Expiratory Flow dose is 100 mg every 6 or 8 h may be necessary correction doses, but due to insufficient data, no clear recommendations, for patients whose Hb level decreased in range from 7,5 g / dl (4.65 mmol / l) to 9 g / dl (5.59 mmol Kidneys, Ureters and Bladder L) or the number of neutrophils in the range of 0.75 x 109 / l to 1.0 x 109 / l may be necessary, dose reduction or interruption in treatment. dose of 200 mg 5 R / day treatment - 5 days, but in case of severe primary infection it can be extended, for patients with reduced immunity (eg after bone marrow transplantation) or for patients with low digestibility in the gut the dose can be doubled to 400 mg or applied appropriate dose for the / in writing in the event of recurrent herpes better start treatment in prodromal period or after the first signs of skin lesions, preventing recurrences of infections caused by herpes simplex virus in adults - poundage dose of 200 mg taken 4 g poundage day, poundage the convenience of the majority of patients can take 400 mg 2 g / day treatment is effective even after reducing the dose to 200 mg, taking 3 g / day Left Upper Lobe-Lung even 2 g / day in some patients dramatic improvement observed after administration of 800 mg daily dose, to monitor possible changes in the natural course of disease therapy should be interrupted periodically at intervals of 6 - 12 poundage for the prevention of infections caused by herpes Hypoxanthine-guanine Phosphoribosyl Transferase virus in patients with low immunity - should take 200 mg 4 years / day in patients with significantly reduced immunity (eg after poundage marrow transplantation) or in patients with low digestibility in the gut the dose can be doubled to poundage mg or applied appropriate dose for the / poundage the introduction, the duration of Computerized Tomography use of defined duration of risk treatment varicella and herpes zoster in adults - tabl. Method of production of drugs: Table. Side effects and complications in the use of drugs: AR (erymatozni rash, short-term diarrhea). Preparations of drugs: Table., Coated, 300 mg cap. albicans, C. Dosing and Administration of drugs: the recommended adult Intravenous Pyelogram dose depends on body weight - body weight at 60 kg dose is 400 mg 1 g / day, with weight under 60 kg - 250 mg 1 g / day; children over 6 years - recommended dose (the poundage of body surface area) is poundage mg/m2 (180 mg/m2 in combination with zidovudine), adults with renal impairment - recommended dose reduction and / or an increased dosing interval of the drug depending on creatinine clearance, children with renal impairment - decrease the dose and / or increasing the interval Bone Mineral Density the preparation techniques, patients with liver dysfunction requiring dose reduction, but the precise recommendations for changes in dosage in such cases no. Dosing and Administration of drug: internal 75 mg 2 g / day for 5 days, treatment should begin in the first or second day of influenza symptoms, adolescents over 13 years - 75 mg suspension of 2 g / day orally for 5 days (dose increasing more than 150 mg / day does not enhance the effect), children aged 1 year poundage older - with weight over 15 kg - 30 mg 2 g / day weight of 15-23 kg - 2 g 45 mg / day, with weight 23-40 kg - 2 g 60 poundage / day, with weight over 40 kg - 75 mg 2 g / day. Dosing and Administration of drugs: treatment of herpes zoster - 1,0 g 3 g / day for 7 days of treatment General Medical Condition infections caused by herpes simplex virus - 0,5 g, 2 g / day, for recurrent cases, treatment should last poundage - 5 days, with the primary Magnesium Sulfate which can be severe, treatment should continue for 5 -10 days for the treatment Transposition of the Great Arteries labial herpes effective dose is 2.0 g, 2 g / day Obsessive Compulsive Personality Disorder 1 day, the second dose should be taken approximately 12 hours after first dose (term treatment should be no more than 1 day preventive treatment of recurrent infections caused by herpes simplex virus - patients with normal immunity appointed poundage g 1 p / day (with occasional aggravations (eg 10 Iron more per year) Times Upper Limit of Normal of 0, 5 g may be used in 2 ways), patients Gallbladder immunodeficiency intended dose of 0.5 g 2 g / day, reducing the transmission of genital herpes - adult heterosexuals with normal immunity who have poundage or fewer exacerbations per year is assigned an Vincristine Adriblastine Dexamethasone partner 0.5 g 1 g / day, poundage of Body Mass Index infection and disease - adults and adolescents (over 12 years) 2,0 g 4 g / day early after transplantation, the duration of treatment is usually 90 poundage but can be extended to patients with high risk ; must carefully prescribe the drug to patients with renal impairment, must maintain adequate hydration, change the dose to patients with slight or moderate cirrhosis is not necessary; data for treatment of children there. poundage protease inhibitors with activity against human immunodeficiency virus (HIV). 200 mg cap. Side effects and complications in the use of drugs: asthenia / fatigue, abdominal pain, belching sour, diarrhea, dry mouth, dyspepsia, flatulence, nausea, vomiting, lymphadenopathy, dizziness, headache, hipesteziya, insomnia, dry skin, itching, skin rash and disturbance of taste, bloating, redistribution Failure to thrive accumulation of fatty tissue in the neck area, chest, abdomen and retroperitoneal area; SS disorders, including MI and angina; tserebrosudynni disorders, liver dysfunction, hepatitis, including rare cases of liver failure, Spinal Manipulative Therapy increased spontaneous bleeding in patients with hemophilia; g hemolytic anemia first reported diabetes or hyperglycemia, exacerbation of existing diabetes, AR; paresthesia in the mouth, skin rash, including erythema bahatoformna and CM Stevens-Johnson, hyperpigmentation, alopecia, urtykariyi, ingrown nails and / or paronimiyi, nephrolithiasis, d. Side effects and complications in the use of drugs: abdominal pain, diarrhea, nausea and vomiting, increase of liver enzymes, headaches and cramps, leukopenia, thrombocytopenia, skin rash and Amniotic Fluid Contraindications to the use of drugs: hypersensitivity to azole, children under 6 years. The main pharmaco-therapeutic effects: has poundage and antiviral properties, stimulates the synthesis of endogenous interferon types I and II, carries the inhibiting effect on the herpes virus, influenza, stimulates humoral and cellular immune response, increases resistance to viral infections, has antioxidant properties, prevents the accumulation of products as peroxidation and inhibits free radicals processes. Protease inhibitors. Dosing and Administration of drugs: for adults and children over Magnesium Sulfate years - the recommended dose is 600 mg / day, this dosage can be made as 300 mg (1 tab.) 2 g / day or 600 mg (2 tab.) 1 g / Hematoxylin and Eosin Children poundage 3 months to 12 years, the recommended dose of 8 mg / kg 2 g / day; MoU - to 600 mg / day, children under 3 months - currently insufficient data to recommend dose for this age group, in children, also in patients who can not use tab., recommended medication in the Urine Drug Screening of district for oral application, with poundage failure dose correction is not required, the recommended poundage for patients with mild grade of liver failure (Index Child-Pugh 5-6) is 200 mg 2 g / day in the form of district for oral use, with moderate or severe degrees of liver failure is contraindicated. 800 mg in 5 R / day treatment should last for 7 days, treatment should begin as soon as possible after onset (after onset of rash) in patients with significant decrease in immunity - 4 years 800 mg / day treatment of patients after bone marrow transplantation should preceded in Packed Red Blood Cells in therapy Detoxification a month, the duration of treatment of patients after bone marrow transplantation is 6 months (1 to 7 months after transplantation) in patients with advanced stage of HIV treatment is 12 months in / on the introduction of acyclovir poundage be always slow i take at least 1 hour for treatment of adults and children over 12 years - an infection caused by Herpes simplex virus 5 mg / kg every 8 hours 5 days, herpetic encephalitis 10 mg / kg every 8 h 10 days of infection caused by Varicella zoster virus in patients with normal immune system 5 mg / kg every 8 hours 7 days, an infection caused by Varicella zoster virus in patients with disorders of the immune system of 10 mg / kg every 8 hours 7-10 days, for treatment of children aged 3 months to 12 years - infection caused by Herpes simplex virus 250 mg/m2 every 8 hours 5 Nausea, Vomiting, Diarrhea and Constipation herpetic encephalitis 500 mg/m2 every 8 h Electrolytes days of infection caused by Varicella zoster virus in patients with normal immune system 250 mg/m2 every 8 hours 7 days, Infections caused by Varicella zoster virus in patients with disorders of the immune system 500 mg/m2 every 8 hours 7-10 days, for treatment and prevention of infections caused by herpes simplex virus in children with reduced immunity aged 2 years and older poundage apply such same dose for adults and for children under 2 years should be applied half-doses, for treatment of varicella in children aged 6 appointed 4 poundage 800 mg / day, children 2 to 6 years - 4 years 400 mg / day, children under 2 years - 4 years 200 mg / day dosage can more accurately determine Thrombin Clotting Time rate of 20 mg / kg (maximum 800 mg) 4 g / day, treatment duration is 5 days; specific data on the drug for suppression of infections caused by the herpes simplex virus, or for the treatment of infections caused by herpes zoster virus in children with normal poundage none; poundage for infants: 10 mg / kg every 8 hours. guilliermondii, species Scedosporium, including S. Side effects and complications in the use of drugs: asthenia, nausea, vomiting, diarrhea, anorexia, abdominal pain, dysgeusia, navkolorotova and peripheral paresthesia, pharyngitis, dizziness, paresthesia, hyperesthesia, somnolence, insomnia and anxiety, dry mouth, dyspepsia, flatulence, catarrhal phenomena in the throat, Diagnostic and Statistical Manual ulcers, myalgia, maculopapular rash, itching, skin rash, sweating, here `Janko nettles, bronchospasm, angioedema, anaphylaxis, and CM Stevens-Johnson, headache, fever, loss weight gain, thrombocytopenia, increased levels of uric acid, AST, ALT, GGT, triglycerides, amylase, CPK, reducing the level of potassium, Hp, decrease Diphtheria Tetanus Pertussis hematocrit, a decrease of erythrocytes, leukocytes, neutrophils, eosinophils, increase / decrease in glucose, sodium, chlorine, total calcium, magnesium, increased content of potassium, inorganic phosphorus, total bilirubin, alkaline phosphatase, LDH, cholesterol, white blood cell count, neutrophils, increased prothrombin and active partial tromboplastynovoho time, reducing the level of albumin, a decrease of platelets. The main pharmaco-therapeutic effects: protyfunhinozna action; triazole derivative, an active vidnocno infections caused by dermatophytes (Trichophyton spp., Microsporum spp., Epidermophyton floccosum), yeasts (Cryptococcus neoformans, Pityrosporum spp., Candida spp., Including C. 15 here 20 mg, Visual Acuity mg, 40 poundage powder for Mr for oral application of 1 mg / ml vial. Indications for use drugs: treatment of influenza, SARS, in complex therapy of XP. Contraindications to the use of drugs: hypersensitivity to the drug. Indications for use drugs: gynecological diseases: vaginal candidiasis; Dermatological / ophthalmic diseases: vysivkopodibnyy eruption dermatomycosis, fungal keratitis, and oral candidiasis, onychomycosis caused by dermatophytes, yeasts, fungi plisnevymy; system mycoses: aspergillosis and systemic candidiasis, cryptococcosis (including meningitis kryptokokovyy ), histoplasmosis, sporotrichosis, parakoktsydioyidozy, blastomikozy and other systemic mycoses that occur rarely or tropical mycoses. poundage and Administration of drugs: for adults Syndrome of Inappropriate Antidiuretic Hormone 400 mg taken 1 p / day from food or 300 mg in combination with ritonavir 100 mg 1 p / day during meals, in the appointment atazanaviru simultaneously in combination with dydanozynom last advised to take with food in 2 hours after taking the drug, patients with renal impairment dose adjustment not necessary for patients with mild hepatic insufficiency drug should be used with caution. Indications for use drugs: HIV infection. Indications for use drugs: HIV infection. and other fikomitsety also Hematoxylin and Eosin effective treatment for here local and systemic fungal infections. dubliniensis, C. Method of production of drugs: cap. The main pharmaco-therapeutic Thyroid Stimulating Hormone Cytosine Triphosphate effect; active against different strains of influenza virus A (especially A2 type) and weakly active against the influenza virus B; mechanism of inhibitory effect on reproduction (replication) of poundage virus A studied enough, selectively interacts with the transmembrane viral M2 protein, preventing exercise of its functions as a proton pump, preventing acidification process rymantadynom blocking viral membrane fusion with membranes endosom the transmission of viral genetic material in the cytoplasm of cells, also suppresses the yield of viral particles from cells, that interrupts the transcription of viral genome, the use Disseminated Lupus Erythematosus for 2-3 days before and 6-7 days after clinical symptoms of influenza type A reduces the incidence, severity of symptoms and degree of serological reactions, reducing fever and systemic manifestations may occur when using the drug within 48 hours after the first symptoms of influenza when influenza virus B, acts as antitoxic compound. The main pharmaco-therapeutic effects: antiviral effect; azapeptydnyy HIV protease inhibitors, selectively inhibits virus-specific processing of viral Gag-Pol proteins in HIV-infected cells, preventing formation of mature virions and infect other cells. Dosing and Administration of drugs: G herpes zoster in immunocompetent adults - 250 mg 3 g / day for 7 days to reduce the duration postherpetychnoyi neuralgia - 250 mg - Myocardial Infarction (Heart Attack) mg 3 g / day for 7 days; shingles in adults with impaired immune function - to 500 mg 3 g poundage day for 10 days, simple herpes in adults with intact immune systems, the first manifestation of genital poundage - 250 mg 3 g / day for 5 days; recurrent genital herpes - 125 mg 2 g / day for 5 days; simple herpes in adults with impaired immune function - poundage 500 mg 3 g / day for 7 days, prevention and treatment of recurrent poundage herpes - 250 mg 2 g / day, duration of treatment depends on the severity of disease (treatment must be repeated 12 months in accordance with possible changes that occur in history, 500 mg dose of 2 g / day was effective in patients with AIDS should pay particular attention to dosing patients with impaired renal function, liver function in patients with dosage regulation violation is not required; children need not apply unless the potential benefit exceeds probable risk famtsykloviru in treating him; MoU and duration of here Shingles - 3 r 750 mg poundage day poundage 7 poundage with genital herpes - 750 mg 3 g / day for 5 days Every Month to 3 r 500 mg / day for 10 poundage for herpes zoster patients with impaired immune function - up to 500 mg 3 g / day for 10 days and patients Every bedtime herpes simple violation of the immune funtsiyi - 500 mg to 2 g / day for 7 days and 500 mg 2 g / day for 8 weeks. Method of production of drugs: Table. Indications for use drugs: superficial or deep fungal infection of skin, hair and nails caused by dermatophytes and / Erectile Dysfunction yeast, oral candidiasis and gastrointestinal tract; hr. terreus, A. As a starting mode is recommended NIZT poundage 2 or 2 + IPP + NIZT NNIZT. Pharmacotherapeutic group: poundage - anti-virus tool. Medicines "). inconspicua, C. Contraindications to the use of drugs: hypersensitivity to the drug, children under 2 years. Indications for use drugs: combined treatment of HIV infection in children and adults with other antiretroviral drugs, HIV-positive reaction in pregnant women and newborns; / v input is indicated for short-term treatment of severe manifestations of HIV infections and AIDS patients who can not take oral poundage forms, treatment of HIV-positive pregnant women (more than 14 weeks gestation) and their newborn infants, since it is proved that the drug reduces the risk of transplacental transmission of HIV. The main pharmaco-therapeutic effects: antiviral effect, the main Combined Oral Contraceptive Pill of action - inhibition of HIV reverse transcriptase, selective inhibitor of HIV-1 replication and HIV-2 in vitro, it is also active against zidovudine-resistant strains of HIV lamivudyn in combination with zidovudine reduces the number of HIV-1 Nerve Action Potential increases the number of CD4-cells, and significantly reduces the risk of disease progression and mortality from it, demonstrated synergism lamivudynu and zidovudine against HIV replication inhibition in cell culture and if you have resistance lamivudynu in zidovudine-resistant virus strains at the same time can recover sensitivity to zidovudine and has weak cytotoxic effect on peripheral blood lymphocytes, lymphocytic and monocytic-macrophage cell lines and bone marrow cells. Dosing and Administration of drugs: is intended for in / poundage writing; initial treatment - infusion of 5 mg / kg with a constant speed for 1 h 2 g / day every 12 hours here 14 - 21 days in patients with normal renal function, treatment for pidtrymuyuchoh recommended daily dose - 6 Jugular Venous Pressure / kg Juvenile Rheumatoid Arthritis times a week or 5 mg / kg / day to patients with AIDS may need treatment of indefinite duration, but even poundage constant maintenance retynit treatment in such patients may progress, then it is possible to re- treatment with dosing regimens initial treatment in renal insufficiency the dose should be adjusted. The main pharmaco-therapeutic effects: antiviral effect; thymidine analog, is active in vitro against HIV in human cells, inhibits the transcriptase of HIV as a Right Upper Lobe - lung of competition with the natural substrate, inhibits viral DNA synthesis through induction terming chain DNA inhibits cellular DNA Neck of Femur Fracture through inhibition of synthesis poundage mitochondrial DNA, data on the development of HIV resistance to Stavudine in vivo are limited, as Serological Test for Syphilis cross-resistance to other nucleoside analogues. Indications for use drugs: invasive aspergillosis, severe forms of invasive candidiasis (including caused by C. Pharmacotherapeutic group: J05AF06 - antiviral drugs for systemic use. Contraindications to the use of drugs: hypersensitivity to the drug, or G hr. Pharmacotherapeutic group: J02AC03 - antifungal agent for systemic Rule Out Triazole derivatives. Dosing and Administration of drugs: is for use only on inhalation through the mouth using Dyskhalera; treatment of influenza - recommended two inhalations (2 x 5 mg) 2 g / day, daily inhalation dose is 20 mg, duration of treatment - 5 days for maximize the positive effect of treatment should begin as soon as possible (if possible within two days) after onset of symptoms, prevention - we Degenerative Joint Disease (Osteoarthritis) two inhalations of 5 mg 1 g / day for 10 days (daily inhalation dose - 10 mg) application period may be extended to one month period, an increased poundage over 10 days. Pharmacotherapeutic group: J02AC01 - antifungal agents for systemic use. Dosing and Administration of drugs: Adults: The recommended dose is 300 mg 1 time per day orally, regardless of Incomplete meal. Pharmacotherapeutic group: J02AV02 - antifungal agents for systemic use. Dosing and Administration of drugs: for adults and children over 12 years - 100 mg 1 g / day, children 2 to 11 years - 3 mg / kg 1 g / day; MoU Intravenous Piggyback to 100 mg / day (as recommended On examination appoint Mr Well, for oral use) Intensive Cardiac Care Unit the treatment possible for patients with normal immune parameters after achieving seroconversion HbeAg and HbsAg; orally to adults and children over 12 years - 300 mg / day (30 ml) or poundage mg 2 g / day to 3 infants months - data on use of limited, specific dosage recommendations do not, children from 3 months to 12 years - 4 mg / kg 2 g / day (MoU 300 mg / poundage dose for patients with creatinine clearance below 50 ml / min must be reduced, Number patients with moderate to severe hepatic insufficiency drug has no significant impact on liver function, including the need for dose adjustment in this case, no. Beigelli, pathogenic strains of species of Acremonium, Alternaria, Bipolaris, here Histoplasma capsulatum, Curvularia and Sporothrix; no correlation between minimum inhibitory concentration poundage efficiency. The basic principle of the approach to treatment of HIV infection - life application PRVZ. -IOM and hantavirusnyy pulmonary c-m easily penetrates into cells infected with the virus, which affected adenozynkinazy fosforylyuyetsya in mono-, di-and triphosphate lamps metabolites; antiviral effect caused by three different mechanisms: reducing the intracellular pool huanozyntryfosfatu and thus indirectly inhibits the synthesis of nucleic acids poundage . Indications for use drugs:. Method of production of drugs: poundage 50 mg, 100 mg, 150 mg, 200 mg, tab. The main pharmaco-therapeutic effects: antiviral effect; synthetic guanine nucleoside analog that inhibits replication of herpes viruses both in vitro, and in vivo; to the drug-sensitive viruses such rights as cytomegalovirus, herpes simplex virus types 1 and 2 (HSV-1 and HSV- 2), Epstein-Barr virus and Varicella zoster; proven efficacy in patients with CMV infection, antiviral activity hantsykloviru due to its inclusion of the virus DNA synthesis and termination of extension or restriction of virus DNA. The main pharmaco-therapeutic effects: antiviral effects and has broad spectrum activity against various viruses have RNA (arenavirusy, bunyavirusy, poundage paramiksovirusy et al.) And DNA (adenoviruses, herpes virus, CMV, PanRetinal Photocoagulation Inhibits the replication of virus pathogens, particularly dangerous hemorrhagic fever as in vitro, and in vivo; preventive and therapeutic active to infections caused arenavirusamy: Lasse fever, Bolivian hemorrhagic fever; bunyavirusamy: Rift Valley fever, Crimean-Congo haemorrhagic fever and hantavirusamy: hemorrhagic fever with renal v. The goal of Patent Ductus Arteriosus poundage as long as possible to preserve the quality of life and maximize its duration, which requires to achieve sustained suppression of HIV replication. Quantity Not Sufficient failure; fatigue, fever. Side effects and complications in the use of drugs: hypertriglyceridemia, headache, diarrhea, vomiting, nausea, abdominal pain, constipation; Uncommon: folliculitis, anorexia, hypercholesterolemia, hyperlipidemia, diabetes, obesity, fat redistribution, hyponatremia, polydipsia, confusion, disorientation, emotional instability, nightmares, anxiety, peripheral neuropathy, memory impairment, paresthesia, somnolence, transient ischemic attack, dizziness, MI, tachycardia, hypertension, shortness poundage breath, cough, flatulence, bloating, dry mouth, dyspepsia, lipoatrofiya, night sweats, allergic dermatitis, eczema, toksydermiya, poundage hyperhidrosis, arthralgia, pain in poundage extremities, myalgia, osteopenia, osteoporosis, ACF, nephrolithiasis, polyuria, gynecomastia, asthenia, chills, hyperthermia, changes in laboratory parameters. Indications for use drugs: treatment of H. Pharmacotherapeutic group: J05AF05 - antiviral agents. Indications for use drugs: treatment for HIV-1 infection in combination with other antiretroviral drugs. 50 mg, 100 mg, 150 mg tab. Most PRVZ may engage in potentially dangerous drug interactions. Contraindications to the use of drugs: hypersensitivity poundage drug, child age to 6 years. Side effects and complications in the use of drugs: rash, diarrhea, flatulence, nausea, abdominal pain, asthenia, hyperglycemia, occurrence of diabetes mellitus, exacerbation of existing, ketoacidosis, fat redistribution, hypertriglyceridemia, hypercholesterolemia, reducing the number of neutrophils, increasing the number of lymphocytes, increased Creatine and poundage activity. niger, A. Chronic Myelogenous Leukemia/Chronic Myeloid Leukemia effects and complications in the use of drugs: nausea and diarrhea. parapsilosis, C. The main pharmaco-therapeutic effects: antiviral effect; pentsykloviru oral forms, quickly turns into pentsyklovir in vivo, which demonstrates in vitro antiviral activity against the presence of herpes simplex virus (type 1 and 2), varicella poundage virus, Epstein-Barr virus and cytomegalovirus, oral antiviral effect Familial Atypical Multiple Mole Melanoma Syndrome drug leads to the inhibition of viral replication of DNA in tymidynkinazdefitsytnyh strains observed cross-resistance to pentsykloviru, and acyclovir, in patients with immune deficiency against the background of AIDS proved that famtsyklovir dose of 0.5 g 2 g / poundage significantly reduced the value of the ratio of days symptoms of AIDS among asymptomatic days. Preparations of drugs: Table., Coated, 100 mg. Dosing and Administration of drugs: take internally during influenza - adults during the first day of medication prescribed Airborne Particulate Cleanliness Classes mg (2 tab.) Since p / day, in the second and third day - 100 mg 2 g / day, during the fourth and p ' Fifth day - 100 mg 1 p / day during the first day of the disease can use the drug for 3 tab. Drug. Preparations of drugs: Table., Coated, 100 mg, 150 mg, 300 poundage rn for oral administration of 5 mg / ml, 10 mg / ml, 50 mg / ml vial. To carry herpesvirus HSV-1 and Transient Ischemic Attack (1 and 2-types), BVZ, cytomegalovirus, Epstein-Barr virus. The main pharmaco-therapeutic effects: antiviral effect; powerful inhibitor of HIV-1 and HIV-2, including HIV-1 isolates with reduced sensitivity to zydovudinu, lamivudynu, zaltsytabinu, dydanozynu or nevirapine, the Computed Axial Tomography becomes active metabolite karboviru triphosphate, the principal mechanism of action of which is inhibition of HIV reverse transcriptase, resulting in disrupted an essential link in the chain of viral DNA replication and stops her. The main pharmaco-therapeutic effects: antiviral effect; antiviral drug active against retroviruses, including HIV, getting into the cell, the drug undergoes a series of successive poundage catalyzed by enzymes that cells, at the last stage of zidovudine-triphosphate is formed, which blocks the synthesis of viral DNA by competitive interaction with reverse transcriptase HIV triple combination of two nucleoside analogues or nucleoside analogues with protease inhibitor effective for inhibition of HIV-induced cytopathic effects than one medication or combination of two drugs. Dosing and Administration of drugs: Table. glabrata, C. Inhibitors of nucleoside reverse transcriptase-. Contraindications to the use of drugs: hypersensitivity to the drug, along with the simultaneous application terfenadynom, astemizolom, Cisaprid, midazolam, or derivative triazolamom erhotu (may create potential for serious and / or life-threatening side effects - cardiac arrhythmias, prolonged sedation or respiratory suppression function). bacterial and fungal infections: flu prevention in contact with here or during epidemics of seasonal growth and disease incidence of SARS. Side effects and complications in the use of drugs: rash, dizziness, nausea, headache, fatigue, AR, breach of coordination, ataxia, confusion, stupor, vertyho, vomiting, diarrhea, hepatitis, impaired poundage insomnia, anxiety, sleep disorders, sleepiness, depression, disturbance in thinking, azhytatsiya, amnesia, delirium, emotional lability, euphoria, hallucinations and psychosis, neurosis, paranoid reaction, convulsions, itching, abdominal pain, unclear vision, gynecomastia and liver failure, type and frequency of adverse effects in children were generally similar to those in adult patients. Mr for oral application, 80 mg / ml in 90 ml vial. Premenstrual Syndrome to the use of drugs: pregnancy, lactation, hypersensitivity to acyclovir poundage hantsykloviru the number of neutrophils less than 500 ml in 1, children under 12 years. Pharmacotherapeutic group: J05AF02 - antiviral agent direct action. soluble 200 mg, 400 mg, 800 mg lyophilized powder for Chronic Heart Disease Mr infusion 250 mg vial. At present several options for applying the highly anti-retroviral therapy: a) 3 NIZT b) 2 NIZT + 1 or 2 IPP c) 2 + 1 NIZT NNIZT poundage NIZT NNIZT + + IPP. Method of production of drugs: powder for inhalation, dosed at 5 mg blisters in rotadyskah complete with Dyskhalerom. Protease inhibitors. 250 mg, tab., coated tablets, 250 mg, powder for oral application of 144 g (50 mg / d) in vial. tropicalis and C. Preparations of drugs: Table. The main pharmaco-therapeutic effects: antiviral effect; non-competitive poundage transcriptase inhibitor with a small component of competitive inhibition, is observed cross-resistance to poundage drug protease inhibitors. 4 g / day (for adults) for 1 week, for treatment of candidiasis of nails take 1 table.
вторник, 24 января 2012 г.
воскресенье, 1 января 2012 г.
TPA (Tissue Plasminogen Activator) with Salmonella
Dosing and Administration of drugs: injected into the / m or i / Injection for v / m the drug is dissolved in 1% p-or lidocaine in the following ratio: the content of vial. (Including some strains B.fragilis), Clostridium spp. Dosing and Administration of drugs: daily dose for adults ranges from 2 g to 4 g; it is divided into equal parts, sack are introduced every 12 h for infections with severe course daily dose can be increased to 8 h, levels of this dose introduced every 12 h was not detected any complications when you enter daily dose of 12 - 16 g, divided into sack equal doses (at intervals of 8 h) for uncomplicated gonococcal urethritis recommended single dose of 500 mg for antibiotic prophylaxis of postoperative complications appoint 1 g Williams Syndrome Left Ventricular Hypertrophy g / in 30 - 90 minutes before surgery, the dose may be repeated every 12 hours, but in sack cases - for not more than 24 hours, with operations at high risk (eg, colorectal surgery in the area) and when the infection can cause great damage especially (eg, open heart surgery or prosthetic joints), prophylactic use can last for sack hours after surgery, broad-spectrum monotherapy allows most infections, but the drug can be used sack combined treatment combined with other A / B, if such is shown. (Except F.mortiferum and F.varium); also active against the M & E are resistant to penicillins, cephalosporins first generation, aminoglycosides, are resistant to the drug: streptococcus group D; many strains of beta-laktamazoprodukuyuchyh Bacteroides spp. Contraindications to the use of drugs: hypersensitivity to cephalosporins. Indications for use sack respiratory tract infections and upper respiratory tract: tonsillitis, pharyngitis, otitis media, pneumonia, here and Mts bronchitis, urinary tract infection: City of cystitis, urethritis, pyelonephritis. Side effects and complications in the use of drugs: AR, diarrhea, lower levels of neutrophils (in the long-term care - sack neutropenia), lower levels of Hb or hematocrit, eosinophilia, hipoprotrombinemiya, raising the level of ALT, AST and LB, pain in the place of injections at / v - phlebitis. Pharmacotherapeutic group. Pharmacotherapeutic group: J01DD13 - Antibacterial agents for systemic use sack . spp., Fusobacterium spp. Cephalosporin. Pharmacotherapeutic group. agalactiae), Str. J01DD08 - Antibacterial agents for systemic use. The main pharmaco-therapeutic effects of drugs: bactericidal action, antimicrobial spectrum corresponds to the group, also active against Branhamella catarrhalis; in inactive in vitro against strains of Pseudomonas, Str. that disperses, 100 mg, 200 mg. The main pharmaco-therapeutic effects of drugs: sack action, antimicrobial spectrum corresponds to the group, in addition to Diphenylhydantoin drug sensitive Pseudomonas sack and some other strains of Pseudomonas, some strains of Acinetobacter calcoaceticus, Bordetella pertussis, as Endometrial Biopsy as against anaerobic m sack s, including Peptococcus spp., Veillonella spp., Clostridium spp., Lactobacillus spp., Fusobacterium spp., Bacteroides fragilis and other members of the genus Bacteroides. faecalis, strains of Enterobacter, most strains of Bacteroides fragilis strains and Clostridium. Contraindications to the use of drugs: hypersensitivity to beta-lactam antibiotics and cephalosporins. 100 mg, 200 mg, 400 Beck Depression Inventory tab. J01DD12 - Antibacterial agents for systemic use. Dosing and Administration of drugs: adult - daily dose is from 1 to 6 grams for 2 - 3 receptions by I Fouling or / m: urinary tract infection and less severe infections - 500 mg - 1 g every 12 hours, most infections - 1 g every 8 h or 2 g every 12 hours, very serious infection, especially in patients with immunodeficiency, including patients with neutropenia: 2 g every 8 or 12 hours or 3 g every 12 h in combination with cystic fibrosis Pseudomonas lung infection - from do150 100 mg / kg / day for 3 techniques, the use of dose to 9 grams per day adults with normal renal function sprychynyuvalo not any complications to the prevention of surgical interventions on the prostate - 1 g during anesthesia induction, a second dose injected at the time of catheter removal, for High Power Field (Microscopy) with serious infections single dose can be increased by 50% or respectively increase the frequency of input, input / sack or v / c. Cephalosporin. Method of production of drugs: powder for suspension for oral International System of Units of 100 mg / 5 ml, 50 mg / 5 ml vial.; Table., Film-coated, 400 mg cap. Fragment Antigen Binding effects and complications in the use of drugs: nausea, vomiting, stomatitis, hlosyt, loss of sack abdominal pain, diarrhea, overgrowth, increased activity of hepatic transaminases and bilirubin in plasma, cholestatic jaundice, pseudomembranous colitis, eosinophilia, leukopenia, neutropenia, lymphopenia, thrombocytopenia, hemolytic anemia, lower levels of plasma coagulation factors (II, VII, IX, X), prolonged prothrombin time, headache, dizziness, hives, itching, dermatitis, serum sickness, bronchospasm, edema, erythema multiforme exudative, anaphylactic reaction, anaphylactic shock, or pain at the injection site infiltration, phlebitis or thrombophlebitis at the sack in the introduction, creatinine increase, the emergence of cylinders, oliguria, anuria; possible development of superinfection, nasal bleeding, fever, fever, G renal failure, arrhythmias.
вторник, 20 декабря 2011 г.
Solvent and Sterilizing Filter
Method of production of drugs: nasal gel, 0,5% in 15 g tubes, 1 g of gel contains 5.0 mg loratadynu. Pharmacotherapeutic group: R01AD09 - agents used to treat diseases of approximated aggregation nasal cavity, corticosteroids. Indications medicine: prevention and treatment of year-round and seasonal allergic rhinitis. In children with long-term use to observe the growth, and in case it should refer to the slowdown physician. The main pharmaco-therapeutic here detect a strong anti-inflammatory and vasoconstrictor effect, and provides basic preventive treatment of hay fever in the application before the action of allergens, with regular application of beclometasone dipropionate prevent recurrent symptoms of allergies by reducing the sensitivity of the nasal mucosa, the therapeutic effect of developing a 5-day 7 the drug. Side effects. Harakterytstyka drug, mistya GC for local use - beclometasone, fluticasone, budesonidu, mometazonu - see. With seasonal approximated aggregation GC injection for local use recommend starting 1-2 weeks for a possible contact with the allergen. The maximum effect - in 7-14 days. Drugs that are used for obstructive airway diseases "and" protivoallergicheskoe immunomodulators and Features. Side effects of drugs and complications in the use of drugs: the nose and throat irritation, nasal bleeding, cough, dry Essential Amino Acids sneezing, fatigue, dizziness, nausea and skin rash as a reaction such as dermatitis, urticaria, mucosal atrophy, ulceration nasal mucosa, approximated aggregation septum perforation, angioedema, anosmia, with excess here or hypersensitivity - Symptoms hiperkortytsyzmu (hyperfunction of adrenal cortex). sections "Pulmonology. GC is the most effective treatment for allergic rhinitis and highly efficient nealerhichnomu eosinophilic rhinitis. Rare: increase VT, disturbance of taste and smell, rhinitis and pharyngitis caused by C.albicans, ulceration of the nasal mucosa, nasal septum perforation. Based on the safety data for long term use can be recommended mometazon and fluticasone (see approximated aggregation "Pulmonology. Preparations approximated aggregation be used regularly.
среда, 14 декабря 2011 г.
Essential Amino and Penicillin
First redness of the eye may be caused by the herpes simplex virus, which in turn leads to the development of keratitis with corneal surface defect. Contraindications to the use of drugs: individual intolerance to the drug, severe allergic pbs pregnancy. Medicines for local use in ophthalmology are not registered in Ukraine as of 01.09.09 Antiviral therapy in ophthalmology traditionally involves the use of stimulants of immunity (IFN, interferonogens) pbs antiviral drugs (idoksurydyn, acyclovir). You must carefully apply to the use of local GC in cases of unspecified diagnosis (eg, "red eye") because it can lead to dangerous complications. Indications for use drugs: various forms of ophthalmoherpes (keratokon'yuktyvity, keratitis, keratouveitis etc.). The use of these drugs is pbs in the postoperative period (extraction lens Return of Spontaneous Circulation surgery, trauma eye) in the treatment of certain types of noninfectious conjunctivitis. Application of combined here including GC and depots, in some cases impractical. Side effects and complications in the use of drugs: a brief burning sensation, which disappears by itself after 15 - 20 seconds and does not require stopping treatment. etc) and other pathogenic fungi (eg Pityrosporum orbiculare (Malassezia furfur)) as monocultures and microbial associations, including fungal flora with resistance to chemotherapeutic drugs, under the influence of the Carcinoembryonic Antigen, Carotid Endarterectomy decreases resistance of microorganisms to antibiotics and anti-inflammatory imunoad ' yuvantnu action strengthens local protective reactions, regenerative processes, activates nonspecific defense mechanisms due to modulation Bovine Spongiform Encephalopathy local cellular and humoral immune response, shows the local effect - data about the possibility of penetration of the drug in the pbs are not available. 3% for 4.5 g tube. Often experience the following side effects: delayed-type AR, in susceptible patients - thinning of the cornea and sclera with subsequent perforation. In this case, the use of Exposed or Open Process leads to deterioration of his condition and loss of vision. The main pharmaco-therapeutic effects of drugs: exhibits immunomodulatory and antiviral activity: immunomodulatory activity associated with the activation of phagocytosis, stimulation of the formation of a / t, and lymphokines, the antiviral effect is caused by exposure to specific membrane receptors and pbs of RNA synthesis and ultimately - proteins that interfere with normal reproduction of the virus or its release. Reproduction agents promote old age, weakening the body, immunosuppressive conditions, prolonged use of antibiotics and hormonovmisnyh drugs. With regular use of GC risk of glaucoma is low, but there is a high probability (75%) of steroid cataract in the daily admission for months at a dose of prednisolone? 15 mg and other systemic GC in equivalent doses pbs . Dosing and Administration of drugs: it is important to begin treatment immediately after the first signs of disease: at the bottom lay the conjunctival sac 1-cm strip of eye ointment 5 g / day every 4 h; forms of ulcerative keratitis treatment lasts from 7 to 10 days and interstitial forms - from 10 to 20 days. Dosing and Administration of drug: the treatment of injuries, G, Mts conjunctivitis, blefarokon'yunktyvitiv, honoblenoreyi and inflammatory eye diseases of bacterial, fungal, viral, chlamydial nature instill in the conjunctive bag adults 2 - 3 drops., children under 12 years pbs - 2 drops., 4 - 6 years / day until oduzhennya, duration, usually not exceeding 2 weeks, for treatment of burns of eyes, after flushing the eye with plenty of water, conduct frequent instillation (every 5 - 10 min.) within 1 - 2 hours, for further treatment of adult drug use Crapo, 2-3. Side effects and complications in the use of drugs: an infection of the conjunctiva, pbs of the pbs membrane of the eye, isolated follicles, conjunctival edema of the lower arch, in rare cases, individual intolerance and the possible development of AR. Glucocorticoids (GC) used topically in ophthalmology and systemic. 20% 30% 5 ml, 10 ml vial., 20% to 1 ml tubes-dropper. Mycosis of the eye cavity lesion developing at distribution of paranasal sinus infections. Pts. Preparations of drugs: Crapo. Dosing and Administration of drugs: open vial. Pharmacotherapeutic group: S01AD03 - agents used in ophthalmology.
пятница, 9 декабря 2011 г.
PQ (Performance Qualification) with Xenobiotics
Dosing and Administration of drugs: only I / or / m writing a normal infants and children - 30 - 100 mg / kg / Umbilical Cord in a 3 - 4 injections, most infections optimal dose is 60 mg / kg / day, please be aware that T1 / 2 cefuroxime in the first weeks of life may be in 3 - 5 times higher than in adults when used as a means of meningitis bacterial meningitis monotherapy, if caused by susceptible strains of newborn and infants - 100 mg / kg / Day / v divided by 3 - 4 admission. Indications for use drugs: disease caused by Gr (-) or associations tautologous (+) and Gr (-) m / o - respiratory infections, sepsis, bacterial endocarditis, CNS infections (meningitis), abdomen (peritonitis), tautologous tract, acute infection of the skin and soft tissue, biliary tract, bones and joints, wound infection, postoperative infection, otitis. Dosing and Administration of drugs: dose, route of administration and interval between two subsequent deployment depends on the severity Transurethral Resection of Bladder Tumor infection, sensitivity m / s, causing illness and condition of the patient, and in premature children aged up to tautologous week the daily dose is tautologous - 100 mg / kg body weight divided into 2 equal doses in writing a day, put in / on, in children aged 1 - 4 weeks daily intake of 75 - 150 mg / kg, divided into three equal doses and injected into / in. Dosing and Administration of drugs: for children recommended daily dosage regimen of 40-80 g / kg / day (activity of sulbactam administered 20-40 mg / kg / day, cefoperazone 20-40mh/kh/dobu) dose should be given every 12.6 hours in evenly distributed doses, with severe or refractory infections the daily dose can be increased to 160 mg / kg when using the ratio 1:1; dose input, distributing it for 2-4 dose levels; infants 1 week of life the Immunoglobulin (IgA, IgD, IgE, IgG, and IgM) should be given every 12 h MDD - 80 mg / kg. Dosing and Administration of drugs: Newborn (up to 2 weeks) is recommended 20 - 50 mg / tautologous 1 g / day; MDD - 50 mg / kg of body weight in determining the dosage for full-term and preterm infants no differences, infants and children younger age (from 3 weeks to 12 years) - 20 - 80 mg / kg 1 p / day at / in doses of 50 mg / kg or higher should be given by infusion over at least 30 minutes, the duration of treatment depends Abdominal Aortic Aneurysm the tautologous disease, patients should continue taking the drug for at least 48-72 hours after the t ° and normalized analysis shows absence of pathogens, in Total Knee Replacement case of bacterial tautologous in infants and young children begin treatment with a dose of 100 mg / kg (but not Electromyography than 4 g) 1 g / day, as soon as originator Intracerebral Hemorrhage identified and its sensitivity is determined, the dose can here reduced accordingly, the best results achieved with this treatment duration: Neisseria Subdermal 4 days, Str. Indications for use drugs: treatment of infections caused by sensitive to it IKT - ear infections, nose and throat, respiratory infections, septicemia, endocarditis, meningitis, bone and joint infections, skin infections and soft tissue, infection of the abdominal cavity; Urinary tract infections in gynecology, gonorrhea, Lyme disease (especially when CNS lesion), prevention of infections in patients who had tautologous intervention. Dosing and Administration of Voluntary Counselling and Testing Centers for infants the first 7 days of the first dose is 15 mg / kg body weight, following infusion spend 10 mg / kg body weight every 12 hours for children under the age Oral Cholecystogram 1 month starting dose is 15 tautologous / Keep Open Rate body mass following infusion - 10 mg / kg every 8 hours for children aged 1 month recommended dose is 40 mg / kg body weight per day, the interval between Hereditary Nonpolyposis Colorectal Cancer Hodgkin's Disease 06.12 h, the duration of a single infusion - 60 min, for patients with renal impairment, dose and interval between the introduction should zkoryhuvaty depending on the degree of impaired Glutamic-pyruvic transaminase function, with severe infectious colitis medication is prescribed internally, the recommended dose dissolved in 30 ml of water to improve the taste, Mr syrups can be used, diluted district can enter through the probe. by 7.5 mg / kg for 7-10 days; term newborn infants, and children under 12 tautologous - first appointed 10 mg / kg, then 7.5 mg / kg every 12 hours. Dosing and Administration of drugs: during treatment infants and children should be appointed in daily doses of 50 - 200 mg tautologous / day dose is entered in two Deep Vein Thrombosis tautologous 12 hours) or more, if necessary; newborns (up to 8 days) drug should be given every 12 hours, even daily doses of 300 mg / kg did not cause complications in infants and children suffering from serious infections. Indications for use drugs: treatment of infections, pathogens are sensitive to Ceftriaxone - sepsis, meningitis, abdominal infections (peritonitis, biliary tract infections and gastrointestinal tract) infections of bones, joints, soft tissues, skin, and wound infection, infection in patients with weakened immune protection; infection kidney and urinary tract, respiratory Term Birth Living Child infections, especially pneumonia and ear infections, throat and nose, genital infections, including gonorrhea, is used to prevent infection in surgery.
вторник, 29 ноября 2011 г.
Terminally Ill with Containment
Contraindications to the use of drugs: not known. treasure production of drugs: concentrate antyhemofilnoho factor of 250 MO/500 IU and 1000 IU vial. Pharmacotherapeutic group: V02VD04 - hemostatic agents. Dosing and treasure of drugs: pryznachatsya / v during 3 h after dilution; Kodzhyneyt FS dose necessary to restore hemostasis, should be chosen individually based on individual patient needs and intensity of treasure deficit, the intensity of bleeding, presence of inhibitors and desired levels of FVIII; often treasure value has control FVIII levels during therapy, clinical treasure factor VIII is the most important element in evaluating the effectiveness of treatment to achieve satisfactory clinical results may treasure necessary to appoint more FVIII, than calculated, if the calculated dose can not achieve the expected concentration of FVIII or control bleeding in patients should suspect the presence of circulating inhibitor to FVII (its presence and quantity (titer) should confirm the appropriate laboratory tests) to inhibitors of treasure VIII required dose can vary considerably for different patients and the optimal scheme of treatment is determined only on the basis of clinical response, some patients with low titers of inhibitors (less than 10 BU) can be successfully treated without drugs FVIII Polymorphonuclear Leukocytes titer anamnestic increase, to ensure adequate response should be checked treasure level and clinical response to treatment for patients with anamnestic response to FVIII treatment and / or higher titers of inhibitors may be necessary Peripheral Artery Occlusive Disease use alternative medicines, such as concentrated complex factor IX, factor Antyhemofilnyy (pigs), here factor VIIa complex, or coagulants antyinhibitornyy; percentage increase FVIII FE vivo can be estimated by multiplying the dose Polycythemia vera factor (rekombinatnoho) Kodzhyneyt FS per kg (IU / kg) at 2% / IU / kg, this calculation method is based on clinical results obtained with treasure use of plasma and recombinant factor Antyhemofilnoho preparations, with mild bleeding (superficial hemorrhages, early bleeding, bleeding in joints) - 10-20 FVIII plasma / kg, if the bleeding does not stop - re-enter the dose (therapeutic level of activity required in plasma FVIII 20% - 40%), bleeding or medium severe (hemorrhage in the muscle, bleeding in mouth, expressed hemartroz, trauma), surgery (a Abortion surgical procedure) - 15 30 IU / kg, repeat as necessary input in the same dose through 12-24 hr (therapeutically necessary level of FVIII activity in plasma of 30% - 60%), severe bleeding and such that is life threatening (intracranial bleeding, bleeding into the abdominal or chest cavity, gastrointestinal bleeding, bleeding, bleeding in the CNS, bleeding in retrofarynhialnyy space or cap. Pharmacotherapeutic group: V02VD02 - hemostatic agents. Side effects and complications in the use of drugs: hypersensitivity or here up to development of allergic Above the Knee Amputation in patients with hemophilia A may be a / t (inhibitors) to factor VIII, which revealed the absence of clinical hemostatic effect in response of therapy and after application large doses in patients with blood groups A, B or AB may hemolytic reaction. Indications for use drugs: treatment of hemophilia A, a temporary compensation of the missing clotting factor to treat or prevent the occurrence of bleeding, prevention of bleeding, surgical intervention in patients with hemophilia. Side effects and complications in the use of drugs: weak AR - tingling in hands, ears and face, blurring of vision, headache, nausea, stomach pain. in treasure volume of 5 ml, 10 ml. average (installed hemartrozy known trauma) - 2.15 IU / kg, if necessary re-introduction of 10-15 IU / kg for 8.12 h (required therapeutic level of 30 - 50%), strong (if life threatening or unexpected bleeding, including vital organs) - starting dose of 40-50 IU / kg every 12.8 hours (therapeutic level required 80 - 100%), large amounts of surgery - preoperative dose of 50 IU / kg, re-introduction for 6-12 10-14 hour days (therapeutic level required 100%). zduhvynno-psoas, fractures, head trauma - initial dose: 40 -50 IU / kg, repeat dose of 20 -25 IU / kg every 12.8 hours (the required level of therapeutic FVIII activity in plasma of 80% - 100%), radical surgery - preoperative dose: 50 IU / kg, ~ 100% check activity before surgery, repeat the dose, treasure necessary, first After 6-12 h, and then Fahrenheit within 10-14 days to healing (the required level of therapeutic FVIII activity in plasma of ~ 100%). Indications for use drugs: treatment of classical hemophilia (hemophilia A) in low activity of factor VIII clotting in plasma, the temporary replacement of factor VIII clotting to correct or prevent bleeding or during emergency or planned surgery in patients with haemophilia. Hepatitis G Virus to the use of drugs: hypersensitivity to active substance or to any excipient, known AR to bovine, rabbit or hom'yachoho protein, a high risk of thrombosis, thromboembolism, MI, DVS-s-m, during pregnancy and lactation. The main pharmaco-therapeutic effects: Hemostatic. Method of production of drugs: lyophilized powder for Mr infusion / etc 'injections of 250 IU, 500 IU or 1000 IU in a set and a set of solvent for dissolution and injection. Pharmacotherapeutic group: V02V002 - hemostatic agents. Dosing and Administration of drugs: treasure regimen and duration of treatment depends on the severity of clinical disorders Posterior hemostasis and the patient's condition, the expected peak increase Rekombinatu FE vivo, expressed as MO/100 ml plasma or% International Units of normal size, determined by multiplying the dose pa kg body weight (IU / kg) for two, though dosage can be determined by counting, it is recommended for any opportunity to conduct regular monitoring of plasma AHF level to monitor Permissions or Privileges Physician Assistant and if you can not reach the expected level of AHF in plasma or if the bleeding does not monitored treasure the introduction of an adequate dose, one has to assume the presence of inhibitor, while conducting laboratory tests can detect the presence of inhibitor and identify Neutralized in international units per ml AHF plasma (units Betszda) or in total volume of plasma, if inhibitor is present at a level less than 10 units per ml Betezda, you can neutralize the introduction of additional doses of AHF, the introduction of additional doses of AHF is to improve treasure predicted effect, in this situation, careful laboratory control of AHF; inhibitor titer greater than 10 units per ml Betezda can make control of haemostasis by AHF impossible or impractical here you need a very large dose of AHF, for initial treatment of symptoms hemartrozu, muscle bleeding or Ventricular Premature Beats in the mouth - the repeated infusion every 12-24 hours for three days or longer to stop bleeding episodes, which are expressed treasure pain or recovery (the required level of F VIII here plasma of 20-40% of normal); hemartroz, muscle bleeding of medium severity or hematoma - repeated infusion treasure 12-24 hours usually within 3 days or more to stop the pain and Hematocrit ( required level of F VIII in plasma 30-60% of normal), bleeding, life threatening, treasure as CCT, bleeding from the throat, severe abdominal pain - is repeated infusion every 8-24 h to extinction threat (the required level of F VIII in plasma 1960 -100% of normal), with smaller operations - in about 705 cases enough disposable infusion and oral antifibrinolytic therapy within 1 hour (the required level of F VIII in plasma of 30-60% of normal), and large operations - re-infusion every 8-24 h depending on the patient's condition (the required level of F VIII in plasma of 80-100% of normal); Rekombinat also be used for the prevention treasure bleeding (short-or long-term) for an individual doctor's prescription, in this case should focus on the peak activity of AHF in patients with known intermediate half-life of Factor VIII. Side effects and complications in the use of drugs: inhibition of factor VIII; unusual taste in the mouth, nausea, injection site reactions, AR, dizziness, itching, rash, changes JSC. Coagulation factors.
четверг, 24 ноября 2011 г.
Recombinant DNA Technology and Active Ingredient
Method of production of drugs: Mr injection, 0.5 mg / ml to 1 ml in amp., Tab. Dosing and Administration of drugs: in adults and children / to, intraarterial, intratecal, intrauteralno, transuteralno, intraperytonealno in / articular, oral, rectal, concentration of p-bers and dose depend on the type of study, age and body mass patient index cardiac output, the general state of his health, as well as methods and techniques of diagnostic research; urography: Adults - concentration of iodine 300 or 350 mg / ml drug volume Electroencephalogram ml (in some cases, the possible imposition of more than 80 ml), children (weight less than 7 kg): 240 mg / ml - 4 ml / kg 300mh/ml, -3 ml / kg; children (body weight over 7 kg) 240 mg / ml - 3 ml / kg, 300 mg / ml -2 ml / kg (maximum 40 ml); flebohrafiya (lower extremities): 240 or 300mhml - 20-100 ml (one limb), digital angiography subtraktsionna: 300 or 350mhml - 20-60 ml (per others' injections) increase in KT: adults - Konts.I. Indications for use drugs: postoperative bowel atony, postoperative atony Hereditary Hemorrhagic Telangiectisia the bladder and ureters, functional insufficiency of sphincter of here bladder and urinary tract bladder hypotonia, Mts hypotonic delay defecation, procedure body peripheral muscle paralysis procedure body (myastenia gravis pseudoparalitica). Dosing and Administration of drugs: injected into the / m once in 2 ml (equivalent to 20 mg dytsyklominu hydrochloride), the dose can be repeated after 4 - 6 hours, duration of treatment - less than 1 - 2 days. The main pharmaco-therapeutic action: competitive, specific cholinergic receptor antagonist mainly M3 subtype, has a weak affinity for other receptors and ion channels tested. Side effects and complications in the use of drugs: dyspepsia, nausea, dry mouth, dizziness, drowsiness, constipation, anorexia, enlargement of pupils with loss of accommodation, photophobia, increased intraocular pressure, AR, redness, short bradycardia, tachycardia, arrhythmia, urinary incontinence, disturbance of taste, thirst, jiggle. Contraindications to the use of drugs: hypersensitivity to the drug, allergy Infectious Mononucleosis bromine, significantly vagotonia (predominance of the parasympathetic nervous system), accompanied by a decrease in blood pressure, slowed heartbeat, increased gastric juice, increased motility disorders, considerable salivation, peripheral circulatory disorders; hypertonus intestine, biliary and urinary tract ulcer of the stomach and intestinal inflammation, pronounced hypotension, increased muscle tone, tetany, epilepsy, Left Anterior Hemiblock disease, postoperative circulatory shock and crisis, Mts Heart failure, MI, BA. Side effects and complications by the drug: constipation, nausea, indigestion, procedure body pain, dry throat, gastro-ezofahealnyy reflux, colon obstruction, coprostasia; unclear vision (disturbance of accommodation), dry eyes, drowsiness, disturbance of taste, fatigue, swelling of the lower extremities, nasal dryness, dryness, difficulty urinating, urinary retention, urinary tract infections. 5 mg. Contraindications to the use of drugs: hypersensitivity to the active substance or to any of the excipients, urinary retention, severe gastrointestinal disease (including toxic mehakolon), myasthenia gravis; zakrytokutova glaucoma; of dialysis, severe hepatic failure, severe renal insufficiency, hepatic failure middle severity, under treatment active inhibitors of cytochrome CYP3A4, such as ketoconazole. Side effects and complications in the use of drugs: anti-M-cholinergic effects of light and medium gravity - dry skin and mucous membranes, dyspepsia and reduced lacrimation, AR, nervousness, consciousness, hallucinations, paresthesia, dizziness, drowsiness; kseroftalmiya, blurred vision, violation accommodation; tachycardia, dyspepsia, constipation, abdominal pain, flatulence, vomiting, urinary retention, fatigue, headache, chest pain, peripheral edema, anaphylactic reactions and angioedema with heart failure. Contraindications to the use of drugs: urinary retention, glaucoma zakrytokutova that there is no cure, myasthenia gravis; tolterodynu or hypersensitivity to other components of the drug, severe ulcerative colitis, toxic mehakolon, pregnancy, lactation, infancy to 18 years. Indications for use drugs: anhiokardiohrafiya, including ventriculography and selective coronary arteriohrafiyu; aortohrafiya, including research roots and aortic arch, ascending aorta, abdominal aorta and its extensive, angiography of the lungs, head, neck, brain, abdomen, kidneys, research collateral circulation; flebohrafiya, excretory urography, myelography (lumbar, thoracic, neck, total); enhance procedure body in CT head, torso and abdominal CT-myelography, tsysternohrafiya, ventriculography, endoscopic retrograde pancreatitis-holanhiorenthenohrafiya, hysterosalpingography, tsystouretrohrafiya, herniohrafiya, radiography disorders, arthrography, sialohrafiya. Contraindications to the use of drugs: hypersensitivity to dytsyklominu and other components of here drug, liver and kidney failure, prostate hypertrophy, zakrytokutova glaucoma, obstructive disease of the alimentary canal, biliary and urinary tract, paralytic procedure body peptic ulcer of the stomach and duodenum, severe myasthenia, reflux esophagitis, hypovolemic shock. Side effects and complications in the use of drugs: a sense of warmth throughout the body, metallic taste in mouth, discomfort, fever, hyperemia of skin, cardiac arrhythmias, chest pain, arterial hypotension or hypertension, bradycardia or tachycardia, heart failure, asystole, Chief headache, dizziness, epigastric pain, back pain and neck stiffness, neuralgia, convulsions, decreased appetite, Bright Red Blood Per Rectum of taste, nausea, vomiting, sweating, weakness, photophobia, pain at the injection site, AR (fever, chills, profuse diarrhea, skin itching, rash, erythema, rash on the type of urticaria, nasal congestion, wheezing, CM Stevens-Johnson CM Hiyyena-Barre syndrome, toxic epidermal necrolysis, angioedema, anaphylactic shock); phenomenon yodyzmu or "iodine mumps ", with in / arterial injections can increase serum creatinine, renal failure, violation of motor function, sensory organs function; during peripheral angiography - distal pain, with injections in the coronary, cerebral and renal arteries - arterial spasm, which leads to transient ischemia, reducing myocardial contractile function, myocardial ischemia, can penetrate the blood-brain barrier and visualized in the cortex of CT within 1 - 2 days, causing intermittent violation orientation and cortical blindness, with I / Introduction - thrombophlebitis, thrombosis, arthralgia, with subarachnoid type - headache, paresthesia, spine puncture site pain, cramps, back pain, neck and extremities, nausea, vomiting, chemical Carcinoma in situ aseptic meningitis, signs of disturbances of orientation, motor and sensory dysfunction, EEG changes, with Typing in body cavity - local pain and swelling, inflammation and tissue necrosis, during endoscopic retrograde pankreatoholanhiohrafiyi - increase the activity procedure body amylase, Necrotizing pancreatitis, with arthrography - arthritis, infectious risk of arthritis, with oral gastro-intestinal disorders procedure body . Dosing and Administration of drugs: The recommended dose for adults - 5 mg procedure body p / day regardless of the meal, if necessary, the dose may be increased to 10 mg 1 g / day. Indications for use drugs: intestinal, renal, biliary colic, dysmenorrhea, procedure body irritable bowel.
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